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Expertise and Interests

• Regenerative/developmental biology & environmental physiology: directing a research program in discovery of physiological mechanisms that mediate morphogenesis during development and tissue repair/regeneration with the focus on aquatic organisms
• STEM pedagogy: modernization of college and K-12 biology curricula; quantitative assessment of teaching & learning in biology; developing interdisciplinary approaches to improve learning in STEM subjects within liberal arts framework
  • PULSE Ambassador; experienced in application of active learning pedagogies to improve effectiveness of biology education
  • Biology of Human Diversity 鈥� history of racist science, social impacts of racism, and biology of human genetic inheritance
  • Development of K-12 human diversity & civics curriculum 鈥� to guide young students in early acquisition of skills in critical analysis as applied to society
  • Development of assessment instruments for evaluation of competency in biology of human diversity in medical & allied health programs
  • Dissemination of biological concepts through accessible lectures for general
• Accessibility: technological innovations and policies to secure access to education and employment for persons with disabilities

Professional Positions

Associate Professor (tenured)

Department of Biology & Environmental Science, Bridgewater College, Bridgewater, VA (2007 鈥� present)

Teaching

Introductory Biology, Human Physiology, Animal/Environmental Physiology, Developmental Biology

• molecular and cellular foundations of organismal biology
• questions-based active learning; emphasis on higher-level processing in evaluation of learning
• guided inquiry-based labs to facilitate development of scientific literacy and skills

Biology of Human Diversity

• critical examination of human genetic variation and pseudoscience of racialism/racism
• Personal Development/Critical Inquiry (General Education)
  • first year seminar course (鈥淓mancipation from mental slavery鈥�); teaching critical evaluation of information and college-level reflective writing through analysis of literature and current events
• Mentored >40 undergraduate research projects (Spring 2009 鈥� Fall 2024)
  • majority of mentored students advanced to graduate or professional programs
• Training and supervising undergraduate student employees (teaching/research assistants)
• Academic advising of ~20 undergraduates/academic Experienced mentor for underrepresented and first-generation-to-college students
• Introduced college-wide town hall gatherings with students 鈥� 鈥�Small Questions with Khurgel鈥�, with the goal of engaging students鈥� awareness and consideration of societal issues

Research

• Environmental and metabolic control of growth and regeneration in axolotls and anurans
• Racialism鈥檚 impact in health professionals鈥� education and practice
• Development of K-12 & undergraduate human diversity and anti-racism pedagogy

Visiting Scientist

MDI Biological Laboratory, Bar Harbor, ME. May 2023 (Sabbatical leave 鈥� 2023)

• Development and regeneration of axolotl musculature

Visiting Scholar

Department of Biochemistry (Laboratory of Dr. Andrea Wills), University of Washington (Sabbatical leave 鈥� 2023)

• Comparative physiology of anurans and salamanders

Visiting Associate Professor of Research

Department of Cell Biology (Laboratory of Drs. C. and B. Thisse), University of Virginia (Sabbatical leave 鈥� 2015)

• Study of early vertebrate embryogenesis and cardiogenesis

Research Scientist

Department of Plastic & Reconstructive Surgery, and Dept. of Microbiology, University of Virginia (2003-2007)

• Led the development of 3D/spheroid culture methods for study of stem cells differentiation and transplantation

Assistive Technology Analyst

Department of Rehabilitative Services, Commonwealth of Virginia (1998-2002)

• Research and design of assistive technologies for rehabilitation of persons with disabilities

Postdoctoral Scientist

Department of Neuroscience, University of Virginia (1996-1997)

• Directed a series of experiments on post-traumatic degeneration and regeneration in mammalian central nervous system

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Ph.D. (1996) University of Toronto; Department of Anatomy & Cell Biology and Program in Neuroscience. Thesis: “Morphological changes in astrocytes in kindling: relevance for epileptogenesis” (advisor: Gwen O. Ivy)

B.Sc. (1990) University of Toronto. Major: Neuroscience

Scientific Publications

Patent

Khurgel M and Katz AJ (2013) Methods of preparing and characterizing mesenchymal stem cell aggregates and uses thereof. United States Patent No. 8,592,209 B2

Invited chapter

1. M Khurgel (2023) Axolotl metabolism: measuring metabolic energy. In: J Currie & A Seifert (eds) Methods in Axolotl Research (Methods in Molecular Biology series), Springer, New 2562:407-415

Refereed journal articles

2. JD Chavez, 鈥�M Khurgel, 鈥� JE Bruce (2016) A General Method for Targeted Quantitative Cross-Linking Mass Spectrometry. PLoS One, 11(12): e0167547
3. SK Kapur, XWang, 鈥�, M Khurgel and AJ Katz (2012) Human adipose stem cells maintain proliferative, synthetic and multipotential properties when suspension cultured as self-assembling Biofabrication 4(2):025004
4. Holler CJ,鈥�, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. (2012) BACE2 expression increases in human neurodegenerative disease. Am J Pathol. 180(1):337-50
5. Amos PJ, 鈥�, Khurgel M, Rodeheaver GT, Peirce SM, and Katz AJ (2010) Human adipose-derived stromal cells accelerate diabetic wound healing: impact of cell formulation and Tissue engineering. Part A 16(5):1595-606
6. Mihaylova V, Green AM, Khurgel M, Semmes OJ, Kupfer GM (2008) Human T cell Leukemia virus I Tax-1 protein sensitizes p53 mutant cell to DNA Cancer research 68 (12): 4843-4852.
7. Parker AM, Shang H, Khurgel M, Katz AJ (2007) Low serum and serum-free culture of multipotential human adipose Cytotherapy 9 (7): 637-646.
8. Katz AJ, 鈥�, Khurgel M, Epstein F, French BA (2006) Serial MRI assessment of human adipose-derived stem cells (HASCS) in a murine model of reperfused myocardial Adipocytes 2 (1): 1-10.
9. Parker AM, Rodeheaver G, Salopek L, Shang H, Khurgel M, Katz AJ (2006) Accelerated wound healing in a murine model with the application of multipotent human adipose derived stem cells. J Am Coll Surg 203:S43
10. Khurgel M and Ivy GO (1996) Astrocytes in kindling: relevance to Epilepsy Res. 26: 163-175.
11. Khurgel M, Koo AC, Ivy GO (1996) Selective ablation of astrocytes with intracerebral injections of alpha-aminoadipate. Glia 16: 351-358.
12. Khurgel M, Switzer RC, Teskey GC, Spiller AE, Racine RJ, Ivy GO (1995) Activation of astrocytes during epileptogenesis in the absence of neuronal Neurobiol. Disease 2: 23-35.
13. Hampton RR, Sherry DF, Shettleworth SJ, Khurgel M, Ivy GO (1995) Hippocampal volume and food-storing are correlated in Brain, Behav. Evol. 45: 54-61.
14. Soullierre J, Bissoon N, Khurgel M, Gurd, JW (1994) Tyrosine phosphorylation of glycoproteins in adult and developing rat J. Neurosci. Res. 37: 507-514.
15. Sherry DF, Forbes MRD, Khurgel M, Ivy, GO (1993) Greater hippocampal size in females of the brood parasitic brown-headed cowbird. Natl. Acad. Sci. (USA), 90: 7839-7843.
16. Khurgel M, Racine RJ, Ivy GO (1992) Kindling causes changes in the composition of the astrocytic cytoskeleton. Res., 592: 338-342.
17. Milgram NW, Yearwood T, Khurgel M, Ivy, GO Racine, RJ (1991) Changes in hippocampal inhibitory processes in rats following recurrent seizures induced by systemic administration of kainic acid. Brain Res., 551: 236-246.

Presentations (selected).

• Bolyard KJ and Khurgel M (2024). Visualizing the evolution of a varied population using Avida-ED. In: Cole M and O鈥橞rien J, Advances in biology laboratory education. Volume 45. Publication of the 45th Conference of the Association for Biology Laboratory Education (ABLE).
• Khurgel M (2023) Axolotl metabolism: interplay between growth and Salamander Research Network, October 2023
• Khurgel M (2023) Metabolism-dependent growth and limb-regeneration in axolotls. EMBO Workshop: Developmental metabolism: flows of energy, matter, and information, September 2023.
• O鈥橞rien A and Khurgel M (2023) Water quality parameters as indicators of axolotl ASB Meeting. *1st place award for excellence in student research
• Ellis N and Khurgel M (2022) Not all axolotls grow the Mid-Atlantic SDB Regional Meeting.
• Khurgel M (2020) Experimental evolution with in silico EMBO/EMBL Symposium: The Organism and its Environment
• Khurgel M (2018) The illusion of races 鈥� human diversity and development of positive identity in middle Presented at the Global Forum on Girls鈥� Education II, Washington, D.C.
• Khurgel M, Cullip MO, Hastings A (2015) Metabolic energy-dependent regulation of stem cell recruitment and differentiation in axolotl limb Stem Cell Biology, Cold Spring Harbor Laboratory, NY
• Khurgel M and Cullip MO (2014) Temperature-dependent regulation of stem cell recruitment in limb Stem Cell Energetics, Berkley, CA
• Hull MJ and Khurgel M (2012) Uncovering the secret of regeneration ASB Meeting.

*Honorable Mention Award for Excellence in Student Research

Professional Development and Service

• Council on Education (Bridgewater College) 鈥� elected faculty representative
• Chair 鈥� Bridgewater College IACUC (2024-25)
• Member – Virginia Educational Development Network (VEDC) Faculty Learning Community, 2024
• Grant Reviewer 鈥� National Science Foundation, 2023
• Peer Reviewer (manuscripts) 鈥� Developmental Dynamics, 2024; Stem Cell Reviews and Reports, 2022
• PULSE Ambassador (2019 鈥� present) 鈥� assisting biology and life science departments with implementation of Vision & Change in Undergraduate Biology Education, and transformation of educational program to inclusive, student-centered, evidence-based teaching and learning
• DEI Committee (Bridgewater College) 鈥� elected faculty representative
• Science outreach 鈥� general public; through Bridgewater College鈥檚 Speaker Bureau; 2007 – present
• Invited educator for Avida 鈥揈D Active LENS Workshop; May 2016
• Fellow 鈥� Avida鈥揈D Active LENS Workshop; June 2015 – NSF-funded program to facilitate teaching and learning principles of evolution
• Pedagogy Project on teaching public discourse 鈥� core faculty; 2014-2015
• Fellow – duPont Summer seminar for Liberal Arts faculty; June 2014
• Fellow 鈥� Shenandoah Valley STEM Collaborative; Spring 2013; exploring strategies to enhance/increase student learning in STEM disciplines
• Organizer 鈥� STEM Teaching Methods Workshop, Bridgewater College, March 2012
• 4-VA conferences 2012, 2013; discussion leader for the breakout session on student preparation 鈥� 2012
• Big Question Faculty Fellow 鈥� Bridgewater College鈥檚 Quality Enhancement Program 鈥� 2012
• Bridgewater College鈥檚 SACS accreditation QEP Committee, 2011-2012
• VAGEP (Virginia Graduate Education Programs) planning conference, 2012
• Mentor/faculty in STEP-STEM Bridge Program 2009, 2010, 2013
• Fellow – Bean Beetle Curriculum Development Workshop, Emory U, June 2011

(NSF-funded program to develop and introduce guided inquiry laboratories in undergraduate biology courses)

• Faculty adviser 鈥� Bridgewater College Interfaith Board

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Awards/Fellowships

• MDI Biological Laboratory Visiting Scientist grant 鈥� May 2023
• Faculty research grant, Bridgewater College – 2008, 2010, 2011, 2014, 2015, 2016, 2020 鈥� 2024
• JW Martin Summer Research Institute grant and TREB awards 鈥� supervisor of undergraduate research (2011, 2014 鈥� 2023)
• 2014 duPont Summer Seminar scholarship 鈥� undergraduate faculty development
• 2011-12 L. Mednick Memorial Fellowship (research) – Virginia Foundation for Independent Colleges
• 2009 NIH-ARRA grant – Co-investigator

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Membership in Professional Societies

• American Association for the Advancement of Science (AAAS)
• Society for Developmental Biology
• International Society for Regenerative Biology